Comprehensive Framework for Rational Prescribing: The book emphasizes a structured and evidence-based approach to prescribing, tailored specifically for the elderly population. This includes detailed insights into age-related physiological and pharmacokinetic changes, as well as practical application of tools such as the Beers Criteria and STOPP/START frameworks to address potentially inappropriate medications (PIMs) and ensure safe and effective medication use.
Focus on Polypharmacy Management and Deprescribing: Addressing polypharmacy—a prevalent issue among older adults—the book provides strategies for mitigating its risks, such as adverse drug reactions (ADRs), medication nonadherence, and healthcare costs. It highlights deprescribing as a patient-centered intervention, using tools like comprehensive medication reviews (CMRs) to discontinue unnecessary or harmful medications.
Integration of Personalized Medicine and Pharmacogenomics: Personalized medication management is explored through precision medicine principles, integrating genetic predispositions, comorbidities, drug history, and functional status. The book demonstrates how pharmacogenomic insights, such as identifying genetic variations in drug-metabolizing enzymes, can reduce ADRs and enhance therapeutic outcomes in high-risk elderly populations.
Ethical and Legal Considerations in Elderly Care: The book addresses the ethical complexities of prescribing for the elderly, including informed consent, shared decision-making, and end-of-life care. It stresses the importance of patient autonomy and collaborative care while ensuring compliance with legal and ethical standards in managing medications for vulnerable elderly patients.
Practical Tools and Real-World Case Studies: The inclusion of case studies provides actionable insights into evidence-based prescribing practices. These examples illustrate managing challenges such as asymptomatic bacteriuria, drug-induced cognitive impairment, and ADRs in the context of polypharmacy. The book also explores innovative tools such as the anticholinergic burden scale to improve decision-making.

About the author

Books by ARVIND MATHUR

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ICP/API Guidelines on Rational Prescribing Practices in the Elderly