Heart failure is a major public health problem that is growing across the world and has become a leading cause of hospitalization in the elderly with more than 1 million admissions every year in the US medicare population. Clinicians frequently encounter patients with heart failure in their everyday practice. The prognosis of heart failure, although much improved (in recent years), still remains worse than many cancers. Appropriate treatment designed to prevent and treat heart failure can significantly reduce the associated high morbidity and mortality. However, with the expanding pharmacopeia of drug therapy and the use of various devices, selection of an appropriate therapeutic strategy for a given patient has become quite challenging. This comprehensive monograph on Drug and Device Selection in Heart Failure is designed to provide a series of state-of-the-art reviews on the most important topics that will help educate and equip the clinician with the appropriate knowledge-base to select the best evidence-based therapy for patients with heart failure.