A book, which is written for the aid of professionals as a quickbench reference, when such a book’s first edition is well received, it increases the responsibility of authors and editors to the next level, as the expectation of the readers for a more concise and accurate presentation in the future editions. Lot of water has flown down the river of knowledge in assisted reproduction from last 4 decades and only past decade has seen some of the fabulous research gone into making ART more accountable, successful and safe, not only for the patients seeking the help of professionals to conceive but also for the professionals to elevate and try the best possible techniques backed by thousands of human hours of bench research to precise therapeutic applications.