World clinics are periodicals of evidence-based reviews proposed as a source of comprehensive, state-of-the-art reviews written by experts. Each issue of “World Clinics Dermatology” would focus on a single theme covering topics that are relevant to clinical understanding and decision-making. Each topic would be developed to reflect the current evidence, research, existing guidelines and recommendations as well the clinical experience of experts. The current issue of World Clinics in Dermatology 2019 gives a wide insight into older and newer exciting broad-spectrum topical antifungals.