While some practitioners have the opportunity of going through formal training in IUI, many more must rely on information gathered from diverse and informal sources. Such information might not be comprehensive or easy to assimilate. The aim of this book is to present relevant information in an easy-to-read manner from diverse sources. A book, such as this, was long overdue about two decades ago; following its first print-run, there was a glut of intrauterine insemination (IUI) books in the Indian medical publishing space—but this book has stood the test of time and is now in its fourth edition. It provides the basic knowledge required to set-up and run an efficient IUI clinic. IUI is less invasive and cheaper than many other assisted conception treatments such as in vitro fertilization (IVF). Various cadres of medical practitioners offer the treatment in a variety of settings. The decision to write this book was based on the fact that there was no comprehensive source of information worldwide on the conduct of IUI. Rather, practitioners had to obtain disjointed information from several sources, leading to a great variability in the practice and results of the treatment. I assembled a team of highly qualified professionals, and we succeeded in bringing together most of what is presently known about IUI. We were vindicated in our decision with the first three editions selling in over 40 countries worldwide. The book is practice oriented. Although we have discussed the theoretical basis of the subject and the various schools of thought in each chapter, we have still provided practical guidelines such that the reader should become very confident and competent in providing this treatment. Although the book is directed primarily toward healthcare professionals, non-medical persons have found the book easy to read and patients find the information provided in the book to be very useful. Furthermore, the issues raised in some chapters concern not only IUI but also many other assisted conception treatments. Such common topics include ovarian stimulation, ultrasound scanning, power Doppler, laboratory aspects of treatment and complications and regulation of assisted reproductive techniques. I have noted copies of the first three editions in a number of libraries I have visited since their publication; it is also a good reference book.