Orthopedic surgery stands at a transformative crossroads, where precision, personalization, and technological innovation are reshaping conventional practices. One of the most significant advancements in recent years is the integration of robotic technology into total knee arthroplasty (TKA). Once considered futuristic, robotic-assisted knee replacement has now become an essential and evolving aspect of modern surgical care, offering improved accuracy, consistency, and patient outcomes. As orthopedic surgeons who have navigated the transition from traditional to technology-driven arthroplasty, we have experienced firsthand the challenges, questions, excitement, and promise that come with adopting robotic surgery. With this book, "A Comprehensive Guide to Robotic Knee Arthroplasty," aims to bridge the knowledge gap and provide a complete, practical, and unbiased guide for all those navigating this new landscape—be it residents in training, early-career surgeons, or seasoned practitioners. This book was conceived in response to a genuine need for a single, authoritative resource that not only explains the mechanics of various robotic platforms but also contextualizes their use in real-world clinical scenarios. It is not merely a compilation of theoretical chapters; rather it represents the shared experience of orthopedic surgeons who have collectively performed thousands of robotic knee surgeries. It brings together the knowledge and insights of contributors who are innovators, educators, and front-line clinicians deeply engaged with this technology on a dayto- day basis. Throughout this book, a conscious effort has been made to keep the content evidence-based, yet clinically oriented and easy to navigate. The chapters begin with the evolution and rationale behind robotic TKA and gradually unfold into detailed discussions on different robotic systems—CUVIS, MISSO, MAKO, VALYS, CORI, ROSA, and more. Each system is examined with a focus on its unique features, operational workflow, indications, benefits, limitations, and clinical outcomes. Comparisons between systems are drawn when relevant to aid in practical decisionmaking. In a field as dynamic as robotic knee arthroplasty, knowledge must evolve in tandem with technology. We hope this book will serve not only as a reference but also as a companion—one that instills confidence, encourages critical thinking, and ultimately contributes to better outcomes for patients worldwide.